Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp176 | Cell biology: osteocytes | ECTS2014

Effects of osteocyte apoptosis and mechanical strain on osteoblast proliferation and migration

Ko Seong-Hee , Lee Hee Su , Baek Kyunghwa

There are several evidences that osteocyte plays a critical role in bone remodeling. Healthy or apoptotic osteocytes can send signals to other bone surface cells like osteoblasts, osteoclasts, osteoclast precursors and bone lining cells through their networking in canaliculi. Therefore, to determine the role for osteocytes in bone remodeling, we examined the effect of healthy and apoptotic osteocytes on osteoblasts proliferation and recruitment. In addition, the effects of mec...